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Therapy Trends
 reports deliver critical and unbiased intelligence derived from in-depth interviews with the world’s foremost thought leaders on the current and future treatment landscapes in major disease areas. Research is focused on the major battlegrounds for market share and answers critical business questions about potential product positioning and competitiveness. Through continuous monitoring and frequent re-engagement with stakeholders, the FirstWord Therapy Trends analyst team delivers quarterly updates with each report ensuring insights remain current and relevant.

  • Rheumatoid Arthritis: KOL Insight [2018]
    Learn More Rheumatoid Arthritis: KOL Insight [2018]
    How is Olumiant impacting the RA treatment landscape? After several years on the US market, the availability of Pfizer’s Xeljanz in the EU is generally welcomed by KOLs; however, Eli Lilly/Incyte’s Olumiant...
  • Head and Neck Squamous Cell Carcinoma: KOL Insight [2018]
    Learn More Head and Neck Squamous Cell Carcinoma: KOL Insight [2018]
    The HNSCC armamentarium is rapidly evolving. Where will IO move next? BMS’ Opdivo and Merck & Co.’s Keytruda have transformed the second-line therapy of recurrent/metastatic head and neck squamous cell...
  • Glioblastoma: KOL Insight [2018]
    Learn More Glioblastoma: KOL Insight [2018]
    Are novel therapies set to revolutionise glioblastoma? There has been little progress in the treatment of glioblastoma (GBM) for decades, and management of patients continues to remain challenging. ​N​ovel treatment...
  • Acute Myeloid Leukaemia: KOL Insight [2018]
    Learn More Acute Myeloid Leukaemia: KOL Insight [2018]
    How will four newly approved therapies transform treatment of AML? For decades, there were no approved treatments for acute myeloid leukaemia (AML) other than chemotherapies. The past year has witnessed the approval of...
  • Targeted Therapies in Asthma: KOL Insight [2018]
    Learn More Targeted Therapies in Asthma: KOL Insight [2018]
    Can new biologics breathe fresh competition into the targeted asthma treatment landscape? The severe asthma treatment landscape is evolving. Near-term debates will focus on how best to use currently approved treatments,...
  • Melanoma: KOL Insight [2017]
    Learn More Melanoma: KOL Insight [2017]
    Are novel therapies set to revolutionise malignant melanoma? Despite advances in the treatment of malignant melanoma (MM), demand still persists for improved modalities and outcomes. Newer targeted and immunotherapy...
  • Multiple Sclerosis: KOL Insight [2017]
    Learn More Multiple Sclerosis: KOL Insight [2017]
    How will Ocrevus reshape the MS treatment landscape? A multitude of recent approvals and launches are changing the way MS is treated, but what does the future hold? Key opinion leaders (KOLs) are excited about...
  • Alzheimer's Disease: KOL Insight [2017]
    Learn More Alzheimer's Disease: KOL Insight [2017]
    Do KOLs see a future for beta-amyloid as a target in Alzheimer’s? Despite the inexorable attrition rate, both big pharma and small biotechs continue to invest in Alzheimer’s disease R&D. Is the amyloid...
  • Prostate Cancer: KOL Insight [2017]
    Learn More Prostate Cancer: KOL Insight [2017]
    How will established and emerging agents reshape the prostate cancer treatment landscape? A multitude of novel therapies have been approved for prostate cancer over the past ten years, but what does the future hold? Key...
  • Ulcerative Colitis: KOL Insight [2017]
    Learn More Ulcerative Colitis: KOL Insight [2017]
    Will oral therapies transform the treatment of ulcerative colitis? With Pfizer’s Xeljanz (tofacitinib) pending approval in the US, new oral therapies are set to transform the ulcerative colitis (UC) treatment...
  • Colorectal Cancer: KOL Insight [2017]
    Learn More Colorectal Cancer: KOL Insight [2017]
    Will new targeted therapies transform the treatment of colorectal cancer? Checkpoint inhibitors continue their march into multiple areas of oncology, and are now approved as treatments for colorectal cancer. But while...
  • Type 2 Diabetes Mellitus: KOL Insight [2017]
    Learn More Type 2 Diabetes Mellitus: KOL Insight [2017]
    Will novel therapies transform the treatment of type 2 diabetes? The treatment of type 2 diabetes mellitus has evolved in recent years with introduction of new classes of molecules. While the wide array of treatment...
  • Atopic Dermatitis: KOL insight [2017]
    Learn More Atopic Dermatitis: KOL insight [2017]
    Will targeted therapies transform the treatment of atopic dermatitis? New targeted treatments look set to transform the treatment of moderate to severe atopic dermatitis. As Dupixent (dupilumab; Regeneron/Sanofi) gains...
  • NSCLC: KOL Insight [2017]
    Learn More NSCLC: KOL Insight [2017]
    How will immunotherapy combination regimens impact the NSCLC treatment landscape?  The pace of change in NSCLC shows no sign of abating. Developments in immunotherapy continue to take centre stage, particularly in...
  • Bladder Cancer: KOL Insight [2017]
    Learn More Bladder Cancer: KOL Insight [2017]
    How will immune checkpoint inhibitors transform the treatment of Bladder Cancer? Significant progress has been made over the past decade in bladder cancer as a host of new targeted therapies have emerged from the...
  • Chronic Lymphocytic Leukaemia (CLL): KOL Insight [2017]
    Learn More Chronic Lymphocytic Leukaemia (CLL): KOL Insight [2017]
    Will novel targeted therapies establish a place in CLL treatment pathways?  Chemo-immunotherapy regimens incorporating Rituxan/MabThera have traditionally been at the forefront of CLL treatment. How is this all set...
  • Psoriasis: KOL Insight [2017]
    Learn More Psoriasis: KOL Insight [2017]
    Will biosimilar anti-TNFs prevent novel therapies from gaining traction?  As the use of biosimilar anti-TNFs continues to expand access , and lower the costs of, biologic therapies in the treatment for psoriasis,...
  • Renal Cell Carcinoma: KOL Insight [2017]
    Learn More Renal Cell Carcinoma: KOL Insight [2017]
    How will new combination regimens impact the RCC treatment landscape? The treatment of advanced RCC has been transformed in recent years as VEGF, TKI and mTOR inhibitors have taken centre stage. KOLs now argue that the...
  • Multiple Myeloma: KOL Insight [2017]
    Learn More Multiple Myeloma: KOL Insight [2017]
    Will novel therapies transform the treatment of Multiple Myeloma? In recent years, there has been significant progress in the prognosis for newly diagnosed multiple myeloma (MM) patients. While the current range of...
  • Systemic Lupus Erythematosus (SLE): KOL Insight
    Learn More Systemic Lupus Erythematosus (SLE): KOL Insight
    Will novel therapies revolutionise the treatment of SLE? With the approval of GSK’s Benlysta (belimumab) came the dawn of targeted therapy in the treatment of systemic lupus erythematosus (SLE). Roche’s...

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