Will novel targeted therapies change AML treatment pathways?
For decades, chemotherapies have been at the forefront of AML treatment. How is this all set to change within the next few years? Novartis’ midostaurin and Seattle Genetics vadastuximab talirine form part of a rich pipeline, but which drugs stand out to key opinion leaders (KOLs)? Are these agents effective enough to displace chemotherapies and lead to durable remissions? Most importantly, will they improve survival in patients that need it the most?
Learn how KOLs see the market evolving, and how they expect developers to differentiate their pipeline therapies in KOL Insight: Acute Myeloid Leukaemia (AML).
Twelve US and European KOLs give their insight on two off-label marketed products and 16 pipeline programmes. KOLs also provide their candid views on the potential for novel chemotherapies and early-stage pipeline programmes.
Plus: Order the report and you’ll receive three quarterly FirstWord Therapy Trends Update Bulletins free!
“Hopefully, over the next five years, we will first of all see an emergence of widespread availability of these targeted small molecule agents; specifically the FLT3 inhibitors and the IDH1/2 inhibitors, I think they are the most promising compounds.”
EU Key Opinion Leader
“FLT3 inhibitors, IDH inhibitors, venetoclax; those are very real and I think those will come to the market very quickly. The others are perhaps the monoclonal antibodies, I expect those to make it. I think those are more realistic and the other [drugs] are possibilities but a little further behind.”
US Key Opinion Leader
Marketed Therapies (off-label)
KOLs from North America
KOLs from Europe
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Update Bulletins include expert insight and analysis based on FirstWord analyst re-engagement with the KOLs after major events such as product approvals, key data releases and major conferences to deliver the most valuable insights with each update.