KOL Insight: Colorectal Cancer [2020]

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Publication Date:
September 2020
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Multi-user licence
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Therapy Trends KOL Insight: Colorectal Cancer [2020]

KOLs describe the approval of Array Biopharma/Ono/Pierre Fabre's Braftovi in combination with cetuximab for the second-line treatment of patients with BRAF V600E-mutant tumours as practice changing but could it provide wider value? KOLs state that HER2 inhibitors are the most exciting products in early-stage development for the treatment of CRC - why? US and European KOLs critically assess the prospects of launched and pipeline therapies.

Therapy Trends reports give you an edge by delivering actionable intelligence to help you make informed decisions about your product. Based entirely on in-depth interviews with the world's foremost KOLs, Therapy Trends research focuses on the major battlegrounds for market share and answers critical business questions about product positioning and competitiveness.
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Key questions answered

  • The KEYNOTE-177 trial confirmed the value of immunotherapy in MSI-H patients but could this approach expand to meet the needs of the larger MSS population?
  • Despite some misgivings from KOLs, the use of biosimilar bevacizumab is set to expand – why?
  • Why are KOL expectations of further breakthroughs in CRC for EGFR inhibitors low?
  • Despite trial setbacks is there still an opportunity for Bayer's Stirvaga (regorafenib) and BMS' Opdivo (nivolumab) combination in the MSS population?
  • What advantages and benefits do KOLs see for the use of ctDNA, translational oncology and expansion cohort trials in CRC?

Examples of Therapies Covered

Avastin Zaltrap
Cyramza Erbitux
Vectibix Stivarga
Keytruda Opdivo
Lynparza Bavencio

Partial List of Participating KOLs

  • Dr Axel F. Grothey, MD
    Professor of Medicine, West Cancer Center and Research Institutue, OneOncology, Germantown, TN
  • Dr Michael Morse, MD
    FACP, MHS, Professor of Medicine, Duke Medical Center, Durham, NC
  • Dr Jaffer A. Ajani, MD
    Professor of Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
  • Dr Julien Taïeb MD, PhD
    Professor of Medicine, Université Paris Descartes, Paris, France
  • Dr Alberto Sobrero, MD
    Professor of Medical Oncology, IRCCS Ospedale San Martino IST, Genova, Italy
  • Dr Eric Van Cutsem, MD
    Professor of Internal Medicine, Head of the Digestive Oncology Unit, University Hospital Leuven, Belgium
FirstWord PerspectivesWe engage the world's leading key opinion leaders, ensuring the viewpoints delivered are authoritative and consequential. Strict screening criteria ensures high-quality interviews.
FirstWord PerspectivesOur-in house senior analysts and medics leverage their disease area knowledge and market research expertise to identify the key questions and issues.
FirstWord PerspectivesOur reports provide a detailed analysis, based on the candid views of world-renowned KOLs, of how treatment algorithms are likely to evolve over the next 3-5 years.
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